High oil phase pharmaceutical vehicles and sunscreen composition

Details High oil phase pharmaceutical vehicles and sunscreen composition High oil phase pharmaceutical vehicles and sunscreen composition

1986-12-04

1989-03-07

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

424 60, 514937, 514938, A61K 742, A61K 744, A61K 910

Patent

active

048104892

ABSTRACT:
High oil phase pharmaceutical vehicles in the form of an emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises from about 1% to about 10% of an alkylated PVP copolymer, from about 2% to about 10% of an emulsifier, and a solvent system. The solvent system comprises from about 4% to about 20% of a C.sub.4 -C.sub.22 fatty acid, alcohol or ester thereof, from about 2% to about 25% of a glycol ester or diester, and from 0% to about 13% of a branched chain ester of a C.sub.4 -C.sub.22 carboxylic acid. The pharmaceutical vehicles are useful in sunscreen formulations, and especially those containing higher concentrations of benzophenone-3. When such higher concentrations are used, it is advantageous to add up to about 10% of a branched chain ester of a C.sub.4 -C.sub.22 carboxylic acid.

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