High molecular weight polysaccharide fraction from Aloe...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S053000, C536S055100, C536S127000, C536S123000, C536S123100, C536S124000

Reexamination Certificate

active

10332408

ABSTRACT:
A complex, water soluble polysaccharide fraction having potent immunostimulatory activity isolated fromAloe vera. The polysaccharide fraction has an apparent molecular weight above 2 million daltons. Its major glycosyl components are glucose, galactose, mannose and arabinose. The invention further includes pharmaceutical compositions containing the instant polysaccharide fraction, optionally in combination with acceptable pharmaceutical carriers and/or excipents. These pharmaceutical compositions may be used to provide immunostimulation to an individual in need of such treatment by administering to such an individual an effective amount of the composition. The polysaccharide fraction is also useful as a component of dietary supplements and as a standardization component of commercialAloeproducts.

REFERENCES:
patent: 4511559 (1985-04-01), Szendrei et al.
patent: 4735935 (1988-04-01), McAnalley
patent: 6133440 (2000-10-01), Qiu et al.
patent: 6482942 (2002-11-01), Vittori
Qiu et al. ModifiedAloe barbadensisPolysaccharide with Immunoregulatory Activity. Planta Med. Mar. 2000; 66(2):152-6.

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