High molecular weight collagen-like protein polymers

Details High molecular weight collagen-like protein polymers High molecular weight collagen-like protein polymers

1996-05-02

1998-06-30

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 697, 4352523, 43525277, 530356, 5303889, 5303898, 536 235, C12P 2102, C07K 14435, C12N 1512

Patent

active

057732493

ABSTRACT:
Collagen-like polymers having repetitive triads are produced having reduced proline content, where glycine is the initial amino acid and the subsequent amino acids are varied, while retaining at least a minimum percentage of prolines. The resulting polymers have collagen-like properties, but are capable of being produced in unicellular microorganisms at high molecular weights and in high efficiency. The polymers, while retaining collagen-like characteristics, include various novel sequences which impart new characteristics, finding wide use in photographic, medical, structural and fiber applications.

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