High level antioxidant-containing foods

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...

Reexamination Certificate

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C800S298000, C800S317000, C800S317100, C800S317200, C800S317300, C800S317400, C435S410000

Reexamination Certificate

active

07855319

ABSTRACT:
The present invention relates to increasing at least one antioxidant level in a plant or plant product by expressing a polynucleotide that encodes a transcription factor, which is active in a flavonoid pathway. Overexpression of, for instance, a novel and newly-identified gene, the mCai gene, in a plant, results in increased accumulation of chlorogenic acid and other related phenolics, which, in turn, increases the levels of beneficial antioxidant in the plant.

REFERENCES:
patent: 2003/0221213 (2003-11-01), Rommens et al.
patent: 2004/0003434 (2004-01-01), Weeks et al.
patent: 2004/0107455 (2004-06-01), Rommens et al.
patent: 2005/0034188 (2005-02-01), Weeks et al.
patent: 0 154 204 (1994-01-01), None
patent: WO 03/069980 (2003-08-01), None
patent: WO 2005/004585 (2005-01-01), None
Kang et al, Agricultural Chemistry and Biotechnology, Sep. 2006, vol. 49, No. 3, pp. 75-81.
Clarisa Start Column, The St Louis Post-Dispatch, Jan. 7, 1989.
Baumann et al., “The DNA Binding Site of the Dof Protein NtBBF1 is Essential for Tissue-Specific and Auxin-Regulated Expression of theroIBOncogene in Plants”,The Plant Cell, Mar. 1999, vol. 11, pp. 323-333.
Benzie et al., “The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay”,Analytical Biochemistry, 1996, vol. 239, pp. 70-76.
Bürkle et al., “Transport of Cytokinins Mediated by Purine Transporters of the PUP Family Expressed in Phloem, Hydathodes and Pollen ofArabidopsis”, 2003, vol. 34, pp. 13-26.
Cao et al., “Oxygen-Radical Absorbance Capacity Assay for Antioxidants”,Free Radical Biology&Medicine, 1993, vol. 14, pp. 303-311.
Crowley, R. “Determining ORAC”, printed from the internet www.convance.com/analytical
ews—orac.php, Reprinted from the Dec. 2004 Food Product Design Catalog Showcase.
Glazer, Alexander, “Phycoerythrin Fluorescence-Based Assay for Reactive Oxygen Species”,Methods in Enzymology, 1990, vol. 186, pp. 161-168.
Held, P., “Performing Oxygen Radical Absorbance Capacity Assays with Synergy™ HT, ORAC Antioxidant Tests, BioTek Application Notes”, printed from the internet www.biotek.com/products/tech—res—detail.pho?id=161.
Hellens et al., “pGreen: a Versatile and Flexible Binary Ti Vector forAgrobacterium-Mediated Plant Transformation”,Plant Molecular Biology, 2000, vol. 42, pp. 819-832.
Hinchee et al., “Production of Transgenic Soybean Plants UsingAgrobacterium-mediated DNA Transfer”,Bio/Technology, Nature Publishing Company, Aug. 1988, vol. 6, pp. 915-922.
Horsch et al., “A Simple and General Method for Transferring Genes into Plants”,Biological Sciences, Monsanto CompanyMar. 8, 1985, pp. 1229-1231, St. Louis, MO.
Liang et al., “Developmental and environmental regulation of a phenylalanine ammonia-lyase-β-glucuronidase gene fusion in transgenic tobacco plants”,Proc. Natl. Acad. Sci, USA, Dec. 1989, vol. 86, pp. 9284-9288.
Mattila et al., “Basic Composition and Amino Acid Contents of Mushrooms Cultivated in Finland”,J. Agric. Food Chem., 2002, vol. 50, pp. 6419-6422.
Mattila et al., “Determination of Free and Total Phenolic Acids in Plant-Derived Foods by HPLC with Diode-Array Detection”,J. Agric. Food Chem., 2002, vol. 50, pp. 3660-3667.
Miki et al., “Procedures for Introducing Foreign DNA into Plants”,Methods in Plant Molecular Biology and Biotechnology, by CRC Press, Inc., 1993, pp. 67-88.
Niggeweg et al., “Engineering Plants with Increased Levels of the Antioxidant Chlorogenic Acid”,Nature Biotechnology, Jun. 2004, vol. 22, No. 6.
Potrykus et al., “Direct gene transfer to cells of a graminaceous monocot”,Molecular&General Genetics, an International Journal 985, 1985, vol. 199, No. 2, pp. 183-188.
Rice-Evans et al., “Total Antioxidant Status in Plasma and Body Fluids”,Methods in Enzymology, 1994, vol. 234, pp. 279-293.
Rommens et al., “A Transposon Tagging Strategy with Ac on Plant Cell Level in Heterologous Plant Species”,Plant Sciences, 1991, vol. 74, pp. 99-106.
Rommens, et al., “Plant-Derived Transfer DNAs”,Plant Physiology, Nov. 2005, vol. 139, pp. 1338-1349.
Shahrzad et al., “Determination of Some Pharmacologically Active Phenolic Acids in Juices by High-Performance Liquid Chromatography”,Journal of Chromatography A, 1996, vol. 741, pp. 223-231.
Shi et al., “Gibberellin and abscisic acid regulateGAST1expression at the level of transcription”,Plant Molecular Biology, 1998, vol. 38, pp. 1053-1060.
Wayner et al., “Quantitative Measurement of the Total, Peroxyl Radical-trapping Antioxidant Capability of Human Blood Plasma by Controlled Peroxidation”,FEBS 2700, Jul. 1985, vol. 187, No. 1.
Wen et al., “A Universal HPLC Method for the Determination of Phenolic Acids in Compound Herbal Medicines”,J. Agric. Food Chem., 2005, vol. 53, pp. 6624-6629.
Yan et al., “New Construct Approaches for Efficient Gene Silencing in Plants”, Aug. 2006, pp. 1508-1518, vol. 141, Plant Physiology.
Visser, et al., “Expression of a Chimaeric Granule-Bound Starch Synthase-GUS Gene in Transgenic Potato Plants”, 1991, pp. 691-699, vol. 17,Plant Molecular Biology, Belgium.
Guevara-Garcia, et al., “A 42 bp Fragment of thepmas1′Promoter Containing anocs-Like Element Confers a Developmental, Wound- and Chemically Inducible Expression Pattern”, 1998, pp. 743-753, vol. 38,Plant Molecular Biology, The Netherlands.
Jung et al., “The PotatoPLucus Codes for Flavonoid 3′,5′-Hydroxylase”, 2005, pp. 269-275, vol. 110,Theor. Appl. Genet., USA.
Bushman et al., “Two Loci Exert Major Effects on Chlorogenic Acid Synthesis in Maize Silks”,Crop Science, Sep.-Oct. 2002, pp. 1669-1678, vol. 42.
Dixon, Richard A., “A Two-for-One in Tomato Nutritional Enhancement”,Nature Biotechnology, Jul. 2005, pp. 825-826, vol. 23, No. 7, Nature Publishing Group.
Mathews, et al., “Activation Tagging in Tomato Identifies a Transcriptional Regulator of Anthocyanin Biosynthesis, Modification, and Transport”,The Plant Cell, Aug. 2003, pp. 1689-1730, vol. 15, American Society of Plant Biologists.

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