High fidelity DNA polymerase compositions and uses therefor

Details High fidelity DNA polymerase compositions and uses therefor High fidelity DNA polymerase compositions and uses therefor

2011-04-26

2011-04-26

Hutson, Richard G (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S183000, C530S350000, C424S094500

Reexamination Certificate

active

07932070

ABSTRACT:
The subject invention relates to compositions comprising an enzyme mixture which comprises a first enzyme and a second enzyme, where the first enzyme comprises a DNA polymerization activity and the second enzyme comprises an 3′-5′ exonuclease activity and a reduced DNA polymerization activity. The invention also relates to the above compositions in kit format and methods for high fidelity DNA synthesis using the subject compositions of the invention.

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