Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Reexamination Certificate
2011-02-01
2011-02-01
Mondesi, Robert B (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
C435S193000, C435S069100, C435S320100, C536S023200
Reexamination Certificate
active
07879591
ABSTRACT:
Lysophosphatidic acid acyltransferase [“LPAAT”] participates in the second step of oil biosynthesis and is expected to play a key role in altering the quantity of long-chain polyunsaturated fatty acids [“LC-PUFAs”] produced in oils of oleaginous organisms. An LPAAT isolated fromMortierella alpina[“MaLPAAT1”] that is suitable for use in the manufacture of oils enriched in LC-PUFAs in oleaginous organisms is disclosed. Most desirably, the substrate specificity of the instant MaLPAAT1 will be particularly useful to enable increased C18to C20elongation conversion efficiency and increased Δ4 desaturation conversion efficiency in recombinant host cells producing LC-PUFAs.
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Damude Howard Glenn
Xue Zhixiong
Yadav Narendra S.
Zhu Quinn Qun
Chowdhury Iqbal H
E.I. Du Pont de Nemours and Company
Mondesi Robert B
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