High dose ranolazine formulations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424489, 544153, 514255, A61K 948, C07D26530, C07D29500

Patent

active

054727073

ABSTRACT:
Mycophenolate mofetil, mycophenolic acid, and ranolazine can be conveniently manufactured into high dose oral formulations by the hot melt filling of a supercooled mycophenolate mofetil, mycophenolic acid, or ranolazine liquid into a pharmaceutical dosage form. High dose oral pharmaceutical formulations and manufacturing methods therefor are disclosed.

REFERENCES:
patent: 3374146 (1968-03-01), Blicharz et al.
patent: 3705946 (1972-12-01), Dyke et al.
patent: 3853919 (1974-12-01), Mori et al.
patent: 3880995 (1975-04-01), Jones
patent: 3903071 (1975-09-01), Holmes
patent: 4002718 (1977-01-01), Gardella et al.
patent: 4145918 (1979-03-01), Couch et al.
patent: 4321117 (1982-03-01), Kaetsu et al.
patent: 4567264 (1986-01-01), Kluge et al.
patent: 4727069 (1988-02-01), Nelson et al.
patent: 4753935 (1988-06-01), Nelson et al.
patent: 4786637 (1988-11-01), Allison et al.
patent: 4820523 (1989-04-01), Shtohryn et al.
patent: 4842865 (1989-06-01), Durr et al.
patent: 4894235 (1990-01-01), Kohne et al.
patent: 4936074 (1990-06-01), Graham
patent: 5053419 (1991-10-01), Lipton
patent: 5175000 (1992-12-01), Godowski et al.
patent: 5188838 (1993-02-01), Deleuil et al.
patent: 5247083 (1993-09-01), Knox et al.
patent: 5368861 (1994-11-01), Ushimaru et al.
Ewart T. Cole, "Liquid-Filled Hard-Gelatin Capsules", Pharm Technol. 13(9), 124-140 (1989).
Howard, et al., "Drug Release From Thermosetting Fatty Vehicles Filled Into Hard Gelatin Capsules", Drug Dev. & Indust. Phar., 13(6), 1032-1045 (1987).
Thomas, et al., "The Use of Xylitol as a Carrier for Liquid-Filled Hard-Gelatin Capsules", Pharm. Technol. Int. 36-40, Oct. 1991.
McTaggart, et al., "The evaluation of an automatic system for filling liquids into hard gelatin capsules", J. Pharm. Pharmacol. 1984, 36: 119-121.
Smith, et al., "The filling of molten ibuprofen into hard gelatin capsules", Intl. J. of Pharmaceutics, 59 (1990) 115-119.
Walker, et al., "The filling of molten and thixotropic formulations into hard gelatin capsules", J. Pharm. Pharmacol. 1980, 32: 389-393.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

High dose ranolazine formulations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High dose ranolazine formulations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High dose ranolazine formulations will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1372336

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.