Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1994-05-09
1995-12-05
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424489, 544153, 514255, A61K 948, C07D26530, C07D29500
Patent
active
054727073
ABSTRACT:
Mycophenolate mofetil, mycophenolic acid, and ranolazine can be conveniently manufactured into high dose oral formulations by the hot melt filling of a supercooled mycophenolate mofetil, mycophenolic acid, or ranolazine liquid into a pharmaceutical dosage form. High dose oral pharmaceutical formulations and manufacturing methods therefor are disclosed.
REFERENCES:
patent: 3374146 (1968-03-01), Blicharz et al.
patent: 3705946 (1972-12-01), Dyke et al.
patent: 3853919 (1974-12-01), Mori et al.
patent: 3880995 (1975-04-01), Jones
patent: 3903071 (1975-09-01), Holmes
patent: 4002718 (1977-01-01), Gardella et al.
patent: 4145918 (1979-03-01), Couch et al.
patent: 4321117 (1982-03-01), Kaetsu et al.
patent: 4567264 (1986-01-01), Kluge et al.
patent: 4727069 (1988-02-01), Nelson et al.
patent: 4753935 (1988-06-01), Nelson et al.
patent: 4786637 (1988-11-01), Allison et al.
patent: 4820523 (1989-04-01), Shtohryn et al.
patent: 4842865 (1989-06-01), Durr et al.
patent: 4894235 (1990-01-01), Kohne et al.
patent: 4936074 (1990-06-01), Graham
patent: 5053419 (1991-10-01), Lipton
patent: 5175000 (1992-12-01), Godowski et al.
patent: 5188838 (1993-02-01), Deleuil et al.
patent: 5247083 (1993-09-01), Knox et al.
patent: 5368861 (1994-11-01), Ushimaru et al.
Ewart T. Cole, "Liquid-Filled Hard-Gelatin Capsules", Pharm Technol. 13(9), 124-140 (1989).
Howard, et al., "Drug Release From Thermosetting Fatty Vehicles Filled Into Hard Gelatin Capsules", Drug Dev. & Indust. Phar., 13(6), 1032-1045 (1987).
Thomas, et al., "The Use of Xylitol as a Carrier for Liquid-Filled Hard-Gelatin Capsules", Pharm. Technol. Int. 36-40, Oct. 1991.
McTaggart, et al., "The evaluation of an automatic system for filling liquids into hard gelatin capsules", J. Pharm. Pharmacol. 1984, 36: 119-121.
Smith, et al., "The filling of molten ibuprofen into hard gelatin capsules", Intl. J. of Pharmaceutics, 59 (1990) 115-119.
Walker, et al., "The filling of molten and thixotropic formulations into hard gelatin capsules", J. Pharm. Pharmacol. 1980, 32: 389-393.
Berry Stephen
Jarosz Paul J.
Lee Charles
Lee Jung-Chung
Samuels Glenn J.
Freyburg Derek P.
Griffin Ronald W.
Lewis Brian
Lowin David A.
Syntex (U.S.A.) Inc.
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