High dosage topical forms of collagenase

Details High dosage topical forms of collagenase High dosage topical forms of collagenase

1993-11-24

1995-06-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Skin burn or open wound treatment

424444, 424499, 424 9467, 514 59, 514777, A61K 3174, A61K 3754, A61L 1516, A61L 950

Patent

active

054221030

ABSTRACT:
This invention provides pharmaceutical compositions for topical application containing high concentrations of the enzyme collagenase in non-aqueous excipients. The invention also provides a particular excipient, dextran, which is especially useful for admixture with collagenase and which can also be used to advantage with othr pharmaceutically active materials.

REFERENCES:
Harper E., "Collagenases", Ann Rev Biochem, 1980, 49:1063-78.

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