High-density lipoprotein solid-phase precipitation assay device

Details High-density lipoprotein solid-phase precipitation assay device High-density lipoprotein solid-phase precipitation assay device

1994-05-27

1995-09-19

Beisner, William H.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Calorimeter

422 57, 435 11, 436 13, 436 71, C12Q 160, G01N 2100

Patent

active

054513707

ABSTRACT:
An assay device for measuring the concentration of HDL-associated cholesterol in a blood-fluid sample is disclosed. The device includes a glass-fiber sieving matrix capable of separating soluble and precipitated material migrating through the matrix, and a reagent reservoir in the matrix, for releasing a reagent effective to selectively precipitate LDL and VLDL particles, while permitting soluble HDL to migrate through the matrix. The glass fibers are coated with a polymer coating to prevent binding of HDL to the fibers in the presence of the precipitating reagent.

REFERENCES:
patent: 4316916 (1994-05-01), Jones
patent: 4615946 (1986-10-01), Temple
patent: 4987085 (1991-01-01), Allen
patent: 5082626 (1992-01-01), Grage
patent: 5213964 (1993-05-01), Jones
patent: 5213965 (1993-05-01), Jones

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