High-density lipoprotein solid-base assay device

Details High-density lipoprotein solid-base assay device High-density lipoprotein solid-base assay device

1993-03-19

1994-05-31

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving cholesterol

436 13, 436 71, 422 55, 422 56, 422 58, C12Q 160, G01N 3100, G01N 2100

Patent

active

053169166

ABSTRACT:
An assay device and method for measuring the concentration of HDL-associated cholesterol in a blood-fluid sample. The device includes a glass-fiber sieving matrix capable of separating soluble and precipitated material migrating through the matrix, and a reagent reservoir in the matrix, for releasing a reagent effective to selectively precipitate LDL and VLDL particles, while permitting soluble HDL to migrate through the matrix. The glass fibers are coated with a polymer coating to prevent binding of HDL to the fibers in the presence of the precipitating reagent.

REFERENCES:
patent: 5213964 (1993-05-01), Jones
patent: 5213965 (1993-05-01), Jones

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