Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1985-07-26
1988-10-11
Lusignan, Michael R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424439, 426 72, 426 74, 426 94, 426293, 426559, 426621, 426808, A01N 6500, A01K 3578
Patent
active
047770457
ABSTRACT:
A high bran snack, for the prevention of colon cancer, of which a typical formulation is: graham (whole wheat) flour, 40 percent; rice flour, 10 percent; whole wheat bran flour, 50 percent; calcium carbonate, 1.25 percent; reduced iron, 0.013 percent; and riboflavin (as a tracer), 0.02 percent. About 5 ounces of water is added per 80 ounces of dry materials. The dry materials are mixed in a ribbon blender and then fed dry into a cooker extruder. Then the water is added to the mixture in the extruder. The mixture is extrusion cooked and formed in, for example, a twin-screw cooker extruder. Each of the ingredients in the formulation has a processing, nutritional or therapeutic purpose. The extruded pieces are coated with coconut oil and powdered flavorant.
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Bruce, W. R. et al., "Strategies for Dietary Intervention Studies in Colon Cancer", Cancer, vol. 47, No. 5, (Mar. 1, 1981), pp. 1121 to 1125.
Cummings, J. H. et al., "The Effect of Meat Protein and Dietary Fiber on Colonic Function and Metabolism", Am. J. Clin. Nutr. 32:2086-2093, (1979).
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Calandro Thomas P.
Straka Robert
Vanderveer Fred
Kornutik Richard
Lusignan Michael R.
Nabisco Brands Inc.
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