High aspect ratio performance coatings for biological...

Coating processes – Coating by vapor – gas – or smoke

Reexamination Certificate

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C422S130000, C436S043000, C436S518000, C436S514000, C436S524000, C427S491000, C427S569000, C427S576000, C427S237000, C427S238000, C427S255700, C427S575000, C427S253000, C427S239000, C427S230000, C427S236000, C427S249100, C427S099300, C427S318000, C427S255290, C427S255360, C428S036700, C029S890142

Reexamination Certificate

active

07879396

ABSTRACT:
We have developed an improved vapor-phase deposition method and apparatus for the application of layers and coatings on various substrates. The method and apparatus are useful in the fabrication of biotechnologically functional devices, Bio-MEMS devices, and in the fabrication of microfluidic devices for biological applications. In one important embodiment, oxide coatings providing hydrophilicity or oxide/polyethylene glycol coatings providing hydrophilicity can be deposited by the present method, over the interior surfaces of small wells in a plastic micro-plate in order to increase the hydrophilicity of these wells. Filling these channels with a precise amount of liquid consistently can be very difficult. This prevents a water-based sample from beading up and creating bubbles, so that well can fill accurately and completely, and alleviates spillage into other wells which causes contamination.

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