High-affinity RNA ligands for basic fibroblast growth factor

Details High-affinity RNA ligands for basic fibroblast growth factor High-affinity RNA ligands for basic fibroblast growth factor

1995-02-06

1997-06-17

Zitomer, Stephanie W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 912, 935 77, 935 78, C12Q 168, C12Q 1934, C07H 2102, C07H 2104

Patent

active

056398689

ABSTRACT:
Methods are described for the identification and preparation of nucleic acid ligand solutions to basic fibroblast growth factor (bFGF). Included in the invention are nucleic acid ligands to bFGF which are inhibitors of bFGF and 2'-amino-modified RNA ligands to bFGF.

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