High-affinity oligonucleotide ligands to immunoglobulin E (IgE)

Details High-affinity oligonucleotide ligands to immunoglobulin E (IgE) High-affinity oligonucleotide ligands to immunoglobulin E (IgE)

1995-06-06

1997-11-11

Zitomer, Stephanie W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 912, 935 77, 935 78, 536 254, C07H 2104, C07H 2102, C12P 1934, C12Q 168

Patent

active

056865929

ABSTRACT:
This invention discloses high-affinity oligonucleotide ligands to human Immunoglobulin E (IgE), specifically RNA and ssDNA ligands having the ability to bind to IgE, and the methods for obtaining such ligands. The ligands are capable of inhibiting the interaction of IgE with its receptor.

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