High affinity nucleic acid ligands to HIV integrase

Details High affinity nucleic acid ligands to HIV integrase High affinity nucleic acid ligands to HIV integrase

1995-05-16

1996-12-24

Zitomer, Stephanie W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 912, 935 77, 935 78, C07H 2102, C07H 2104, C12P 1934, C12Q 168

Patent

active

055874681

ABSTRACT:
Methods are described for the identification and preparation of nucleic acid ligands to HIV integrase. Included in the invention are specific RNA ligands to HIV integrase identified by the SELEX method. Also included in the invention are specific RNA ligands that are inhibitors of HIV integrase.

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