High affinity nucleic acid ligands of ICP4

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 436501, 536 231, C12Q 168, C12P 1934, G01N 33566, C07H 2102

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active

057957215

ABSTRACT:
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to Transcripion Regulatory Factors, specifically ICP4. Included in the invention are specific ssDNA and RNA ligands to ICP4 identified by the SELEX method.

REFERENCES:
patent: 5475096 (1995-12-01), Gold et al.
Faber et al. Association of the herpes simplex virus regulatory protein ICP4 with specific nucleotide sequence in DNA. Nucleic Acids Research, vol. 14 (15), pp. 6067-6083, 1986.
Cantin et al. (1992) Adv. Exp. Med. Biol. 312:319.
Clusel et al. (1995) Gene Expression 4:301.
Crooke et al. (1992) Antimicrobial Agents and Chemotherapy 36:527.
Draper et al. (1990) Antiviral Research 13:151.
Ellington and Szostak (1990) Abstract of papers presented at the 1990 meeting on RNA Processing, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, p. 226.
Fennewald et al. (1995) Antiviral Research 26:37.
Gao et al. (1990) Antimicrobial Agents and Chemotherapy 34:808.
Gao et al. (1990) J. Biol. Chem. 265:20172.
Hoke et al. (1991) Nucleic Acids Research 216:19.
Jacob et al. (1993) Eur. J. Biochem. 216:19.
Joyce (1989) Gene 82:83.
Joyce and Inoue (1989) Nucleic Acids Research 17:711.
Kinzler and Vogelstein (1989) Nucleic Acids Research 17:3645.
Kmetz et al. (1991) Antiviral Research 16:173.
Kramer et al. (1974) J. Mol. Biol. 89:719.
Kulka et al. (1993) Antiviral Research 20:115.
Kulka et al. (1994) Antimicrobial Agents and Chemotherapy 38:675.
Kulka et al. (1989) Proc. Natl. Acad. Sci. USA 86:6868.
Levisohn and Speigelman (1969) Proc. Natl. Acad. Sci. USA 63:805.
Levisohn and Spiegelman (1968) Proc. Natl. Acad. Sci. USA 60:866.
Oliphant et al. (1989) Mol. Cell. Biol. 9:2944.
Oliphant and Struhl (1988) Nucleic Acids Research 16:7673.
Oliphant and Struhl (1987) Methods in Enzymology 155:568.
Oliphant et al. (1986) Gene 44:177.
Orgel (1979) Proc. R. Soc. Lond. B205:435.
Peyman et al. (1995) Biol. Chem. Hoppe-Seyler 376:195.
Poddevin et al. (1994) Antisense Research and Development 4:147.
Robertson and Joyce (1990) Nature 344:467.
Smith et al. (1986) Proc. Natl. Acad. Sci. USA 83:2787.
Thiesen and Bach (1990) Nucleic Acids Research 18:3203.
Vinogradov et al. (1994) Biochemical and Biophysical Research Communications 203:959.
Whitton (1994) Advances in Virus Research 44:267.

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