High-affinity monoclonal antibodies for botulinum toxin type A

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S413000, C435S007100

Reexamination Certificate

active

07732579

ABSTRACT:
High affinity antibodies for binding epitopes of BoNT/Aand hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/A in a sample.

REFERENCES:
patent: 5932449 (1999-08-01), Emanuel et al.
patent: 6667158 (2003-12-01), Bavari et al.
patent: 7049085 (2006-05-01), Bavari et al.
patent: 7341843 (2008-03-01), Atassi
patent: 2002/0155114 (2002-10-01), Marks et al.
patent: 2004/0175385 (2004-09-01), Marks et al.
patent: 2005/0042775 (2005-02-01), Pomato et al.
patent: 2008/0124328 (2008-05-01), Marks et al.
Bobrovnik, S.A., “Determination of antibody affinity by Elisa. Theory” J. Biochem. Biophys. Methods (2003) 57:213-236.
Friguet, B., A.F. Chaffotte, L. Djavadi-Ohaniance and M.E. Goldberg, “Measurements of the True Affinity Constant in Solution of Antigen-Antibody Complexes by Enzyme-Linked Immunosorbent Assay” J. of Immunological Methods (1985) 77:305-319.
Gill, D. M, “Bacterial Toxins: a Table of Lethal Amounts” Microbiological Reviews (1982) 46(1):86-94.
Sugasawara, R.J., B.E. Cahoon, and A.E. Karu, “The Influence of Murine Macrophage-Conditioned Medium on Cloning Efficiency, Antibody Synthesis, and Growth Rate of Hybridomas” J. Of Immunological Methods (1985) 79:263-275.
Turton, K., J.A. Chaddock, and K.R. Acharya, “Botulinum and tetanus neurotoxins: structure, function and therapeutic utility” Trends in Biochemcial Sciences (2002) 27(11):552-558.
Garcia-Rodriguez, C., R. Levy, J.W. Arndt, C.M. Forsyth, A. Razai, J. Lou, I. Geren, R.C. Stevens, and J.D. Marks, “Molecular evolution of antibody cross-reactivity got two subtypes of type A botulinum neurotoxin” Nature Biotechnology (2007) 25(1):107-116.

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