Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-08-21
1999-02-16
Chan, Christina Y.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 691, 435 912, 4353201, 435 693, 536 235, 536 2431, 530350, C07H 2104, C12N 1511, C07K 14705, C12P 1934
Patent
active
058719300
ABSTRACT:
The invention provides a human high affinity immunoglobulin E receptor-like protein (IGERB) and polynucleotides which identify and encode IGERB. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of IGERB.
REFERENCES:
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Beaven, M.A., et al., "Downstream signals initiated in mast cells by Fc.epsilon.RI and other receptors", Curr. Opin. Immunol., 8:766-722 (1996).
Kinet, J. P., et al., "Isolation and characterization of cDNAs coding for the .beta. subunit of the high-affinity receptor for immunoglobulin E", Proc. Natl. Acad. Sci. USA, 85:6483-6487 (1988).
Adra, C.N., et al., "Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the .beta. subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions", Proc. Natl. Acad. Sci. USA, 91:10178-10182 (1994).
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Bandman Olga
Corley Neil C.
Lal Preeti
Billings Lucy J.
Chan Christina Y.
Incyte Pharmaceuticals Inc.
Tung Mary
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