Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-07
1997-06-03
Zitomer, Stephanie W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 912, 935 77, 935 78, C07H 2102, C07H 2104, C12P 1934, C12Q 168
Patent
active
056356153
ABSTRACT:
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to HIV-1 nucleocapsid. Included in the invention are specific RNA ligands to HIV-1 nucleocapsid identified by the SELEX method and RNA ligands that inhibit the function of HIV-1 nucleocapsid.
REFERENCES:
patent: 5475096 (1995-12-01), Gold et al.
Joyce (1989) Gene 82:83.
Joyce and Inoue (1989) Nucleic Acids Research 17:711.
Ellington and Szostak (1990) Abstract of papers presented at the 1990 meeting on RNA Processing, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, p. 226.
Kinzler and Vogelstein (1989) Nucleic Acids Research 17:3645.
Kramer et al. (1974) J. Mol. Biol. 89:719.
Levisohn and Spiegelman (1969) Proc. Natl. Acad. Sci. USA 63:805.
Levisohn and Spiegelman (1968) Proc. Natl. Acad. Sci. USA 60:866.
Oliphant et al. (1989) Mol. Cell. Biol. 9:2944.
Oliphant and Struhl (1988) Nucleic Acids Research 16:7673.
Oliphant and Struhl (1987) Methods in Enzymology 155:568.
Oliphant et al. (1986) Gene 44:177.
Robertson and Joyce (1990) Nature 344:467.
Thiesen and Bach (1990) Nucleic Acids Research 18:3203.
Rice et al. (1993) Proc. Natl. Acad. Sci. USA 90:9721.
Tanchou et al. (1994) Aids Research and Human Retroviruses 10:983.
Watson et al., Molecular Biology of the Gene, Benjamin/Cummings Publ. Co., Inc., Menlo Park, CA, 1987, pp. 899, 903-905, 956.
Tanchou et al., Aids Research and Human Retroviruses 10:983 (1994).
Allen Patrick
Gold Larry
NeXstar Pharmaceuticals, Inc.
Zitomer Stephanie W.
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