High affinity HIV-1 gag nucleic acid ligands

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 912, 536 231, 536 254, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104, C07H 2102

Patent

active

057260176

ABSTRACT:
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to HIV-1 GAG, Included in the invention are specific RNA ligands to HIV-1 GAG identified by the SELEX method, Also included are RNA ligands that inhibit the function of HIV-1 GAG.

REFERENCES:
patent: 5496938 (1996-03-01), Gold et al.
Anderson (1994) Human Gene Therapy 5:149.
Berkowitz et al. (1993) J. Virology 67:7190.
Buchschacher, Jr. (1993) JAMA 269:2880.
Clever et al. (1995) J. Virology 69:2101.
Joshi et al. (1991) J. Virology 65:5524.
Luban and Goff (1991) J. Virology 65:3203.
Niedrig et al. (1994) J. Virology 75:1469.
Rice et al. (1993) Proc. Natl. Acad. Sci. USA 90:9721.
Tanchou et al. (1994) Aids Research and Human Retroviruses 10:983.
Joyce (1989) Gene 82:83.
Joyce and Inoue (1989) Neucleic Acids Research 17:711.
Ellington and Szostak (1990) Abstract of papers presented at the 1990 meeting on RNA Processing, Cold Spring harbor laboratory, Cold Spring harbor, NY, p. 226.
Kinzler and Vogelstein (1989) Nucleic Acids Research 17:3645.
Kramer et al. (1974) J. Mol. Biol. 89-719.
Levisohn and Spiegelman (1969) Proc. Natl. Acad. Sci. USA 63:805.
Levisohn and Spiegelman (1968) Proc. Natl. Acad. Sci. USA 60:866.
Oliphant et al (1989) Mol. Cell Biol. 9:2944.
Oliphant and Struhl (1988) Nucleic Acids Research 16:7673.
Oliphant and Struhl (1987) Methods in Enzymology 155:568.
Oliphant et al. (1986) Gene 44:177.
Robertson and Joyce (1990) Nature 344:467.
Thiesen and Bach (1990) Nucleic Acids Research 18:3203.
Gura, Science 270:575-577 (27 Oct. 1995).
Hobbs et al., 1973.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

High affinity HIV-1 gag nucleic acid ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High affinity HIV-1 gag nucleic acid ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High affinity HIV-1 gag nucleic acid ligands will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-138276

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.