Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-08-01
2006-08-01
O'Hara, Eileen B. (Department: 1646)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C530S350000, C530S387300, C530S388200, C435S320100, C435S325000, C536S023400, C536S023500, C514S002600, C424S192100
Reexamination Certificate
active
07083950
ABSTRACT:
High affinity fusion proteins (“trapbodies”), capable of binding and inhibiting the activity of soluble, interacting proteins (“SIPs”) are described. The trapbodies are multimers, preferably dimers, of SIP-specific fusion polypeptides which comprise SIP binding domains derived from SIP targets and/or anti-SIP immunoglobulins, as well as multimerizing components.
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Karow Margaret
Stahl Neil
Yancopoulos George D.
Gregg, Esq. Valeta
O'Hara Eileen B.
Regeneron Pharmaceuticals Inc.
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