High affinity chelates containing isothiocyanate groups, useful

Details High affinity chelates containing isothiocyanate groups, useful High affinity chelates containing isothiocyanate groups, useful

1994-07-28

1996-07-23

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Isothiocyanate esters

C07C33128

Patent

active

055391389

ABSTRACT:
The ligands HBED-SCN, HBPD-SCN, and HTDD-SCN are provided which have enhanced ease of reaction with peptides or proteins and which are suitable for chelating with radioisoptopes, especially Indium-.sup.III and Gallium-.sup.67.

REFERENCES:
patent: 3313779 (1967-04-01), White
patent: 4069249 (1978-01-01), Gaudette et al.
patent: 5057302 (1991-10-01), Johnson et al.
patent: 5101041 (1992-03-01), Troutner et al.
patent: 5227474 (1993-07-01), Johnson et al.
patent: 5248764 (1993-09-01), Flanagan et al.
Mathias et al., Nucl. Med. Biol. vol. 15, No. 1, pp. 69-81 (1988).
Mathias et al., Inorg. Chem., 29, pp. 1475-1480 (1990).
Mathias et al., Bioconjugate Chem., 1, pp. 204-211 (1990).
L'Eplattenieer et al., J. Amer. Chem. Soc., vol. 89(4), pp. 837-843 (1967).
Pitt et al., J. Med. Chem., vol. 29, pp. 1231-1237 (1986).

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