Hexapeptides and methods for their production

Details Hexapeptides and methods for their production Hexapeptides and methods for their production

1976-09-15

1978-04-18

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 424177, C07C10352, A61K 3700

Patent

active

040850960

ABSTRACT:
New hexapeptides having the formula X-R-Trp-His(benzyl)-Tyr(benzyl)-Ser(benzyl)-R.sup.1 -Ala-Y wherein X is t-butoxycarbonyl or benzyloxycarbonyl, R is a single bond, His, His(benzyl) or Gln; R.sup.1 is a single bond or Pro and Y is lower alkoxy, amino, lower alkylamino or di(lower alkyl)amino with the proviso that the total number of amino acid units when R and R.sup.1 are combined is one.

REFERENCES:
patent: 3855238 (1974-12-01), Batesky et al.
Schroder et al., The Peptides, vol. I, 1965, Academic Press, New York, pp. 109-111.
Roberts and Caserio, Basic Principles of Org. Chem., Benjamin Inc., 1965, pp. 531, 563-564.
Stewart et al., Solid Phase Peptide Synthesis, Freeman & Co., San Francisco, 1969, p. 12.

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