Hexapeptide amides

Details Hexapeptide amides Hexapeptide amides

1983-05-17

1984-09-18

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

044723059

ABSTRACT:
N-Terminal L-prolyl or D-prolyl hexapeptide amides useful as Substance P agonists and/or antagonists and as analgesics and/or antihypertensives and a process for preparing them are disclosed.

REFERENCES:
patent: 4161522 (1979-07-01), Hamburger
Sandberg et al., J. Med. Chem., vol. 25, No. 9, pp. 1009-1015, 1982.
Chorev et al., Peptides 1980, Proceedings of the Sixteenth European Peptide Symposium, Helsinger, Denmark, Aug. 31-Sep. 6, 1980, edited by K. Bunfeldt, Scriptor, Copenhagen, 1981, paper entitled "Spatial Requirements at the N-Acylating Residue of Substance P Partial Sequence", pp. 451-456.

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