Hexamethyleneiminyl tachykinin receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540597, 540598, C07D40114, A61K 3155

Patent

active

055631339

ABSTRACT:
This invention provides a novel series of substituted hexamethyleneimines which are useful in the treatment or prevention of a physiological disorder associated with an excess of tachykinins. This invention also provides methods for the treatment of such physiological disorders as well as pharmaceutical formulations which employ these novel compounds.

REFERENCES:
patent: 5340822 (1994-08-01), Emonds-Alt et al.
Goulaouic et al, Chemical Abstracts 118:124405k for EP 512,901 (Nov.-1992).
Cecil Textbook of Medicine, 19th ed. (1992), Wyngaarden, M. D. editor, pp. 2075-2078, 2141-2142, and 2199.

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