Hexahydropyrrolo[2,3-b]indole derivatives

Details Hexahydropyrrolo[2,3-b]indole derivatives Hexahydropyrrolo[2,3-b]indole derivatives

1991-11-07

1993-04-27

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548429, C07D48704, A61K 31405

Patent

active

052062600

ABSTRACT:
Mammalian metabilites of the known acetylchloinesterase inhibitor trimethyl-1,3a,8-hexahydro-1,2,3,3a,8,8a-pyrrol[2,3-b]indole-5(3aS,8aR) heptylcarbamate are themselves cholinesterase inhibitors useful in the treatment of various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease and are also useful as analgesic agents in the alleviation of pain.

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