Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-08-21
2007-08-21
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S221000, C540S492000, C540S500000
Reexamination Certificate
active
10566235
ABSTRACT:
The present invention is directed to hexahydrodiazepinone compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
REFERENCES:
patent: 4386090 (1983-05-01), Moinet et al.
patent: 5939560 (1999-08-01), Jenkins et al.
patent: 6011155 (2000-01-01), Villhauer
patent: 6166063 (2000-12-01), Villhauer
patent: 6303661 (2001-10-01), Demuth et al.
patent: 6432969 (2002-08-01), Villhauer
patent: 6699871 (2004-03-01), Edmondson et al.
patent: WO97/40832 (1997-11-01), None
patent: WO98/19998 (1998-05-01), None
patent: WO98/19998 (1998-05-01), None
patent: WO 00/34241 (2000-06-01), None
patent: WO 01/34594 (2001-05-01), None
patent: WO 01/42262 (2001-06-01), None
patent: WO 01/96295 (2001-12-01), None
patent: WO 01/96295 (2001-12-01), None
patent: WO 02/02560 (2002-01-01), None
patent: WO 02/02560 (2002-01-01), None
patent: WO 02/076450 (2002-10-01), None
patent: WO 03/000180 (2003-01-01), None
patent: WO 03/000181 (2003-01-01), None
patent: WO 03/000181 (2003-01-01), None
patent: WO 2003/000180 (2003-01-01), None
patent: WO 03/082817 (2003-10-01), None
patent: WO 2004/007468 (2004-01-01), None
patent: WO 2004/032836 (2004-04-01), None
patent: WO 2004/032836 (2004-04-01), None
patent: WO 2004/043940 (2004-05-01), None
patent: WO 2004/050022 (2004-06-01), None
patent: WO 2004/058266 (2004-07-01), None
patent: WO 2004/064778 (2004-08-01), None
patent: WO 2004/069162 (2004-08-01), None
patent: WO 2004/110436 (2004-12-01), None
patent: WO 2004/112701 (2004-12-01), None
patent: WO 2004/112701 (2004-12-01), None
patent: WO 2005/002530 (2005-01-01), None
patent: WO 2005/011581 (2005-02-01), None
patent: WO 2005/044195 (2005-05-01), None
patent: WO 2005/056003 (2005-06-01), None
patent: WO 2005/056013 (2005-06-01), None
patent: WO 2005/108382 (2005-11-01), None
patent: WO 2005/116029 (2005-12-01), None
patent: WO 2005/123685 (2005-12-01), None
patent: WO 2006/009886 (2006-01-01), None
patent: WO 2006/023750 (2006-03-01), None
K. Augustyns, et al., “Inhibitors of proline-specific dipeptidyl peptidase: DPP IV inhibitors as a novel approach for the treatment of Type 2 diabetes”, Expert Opin. Ther. Patents, vol. 15(10), pp. 1387-1407 (2005).
Hans-Ulrich Demuth, et al., “Type 2 diabetes—Therapy with dipetidyl peptidase IV inhibitors”, Biochimica et Biophysica Acta, vol. 1751, pp. 33-44 (2005).
Biftu Tesfaye
Feng Danqing Dennis
Liang Gui-Bai
Weber Ann E.
Durette Philippe L.
Fitch Catherine D.
Kifle Bruck
Merck & Co. , Inc.
LandOfFree
Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3831481