Hexadentate ligands useful in radiographic imaging agents

Details Hexadentate ligands useful in radiographic imaging agents Hexadentate ligands useful in radiographic imaging agents

1990-12-14

1993-09-07

Stoll, Robert L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

534 10, 534 14, C07F 928, C07F 1300

Patent

active

052430731

ABSTRACT:
The present invention relates to novel preorganized hexadentate ligands suitable for complexing with a radionuclide to form imaging agents for diagnostic purposes. The ligands have the formula: ##STR1## wherein a) R.sub.2 is hydrogen and R.sub.3 is methyl; or R.sub.2 and R.sub.3 together form a methoxy benzene ring.

REFERENCES:
patent: 4444690 (1984-04-01), Fritzberg
patent: 4795626 (1989-01-01), Deutsch et al.
patent: 4925650 (1990-05-01), Nosco et al.

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