Hexacarboxylic acid hexa-amides which form liphophilic complexes

Details Hexacarboxylic acid hexa-amides which form liphophilic complexes Hexacarboxylic acid hexa-amides which form liphophilic complexes

1992-10-20

1994-05-17

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564152, 564156, C07C23306

Patent

active

053129865

ABSTRACT:
Hexacarboxylic acid hexa-amides are described which form new lipophilic magnesium complexes with magnesium ions. The hexa-amides are preferably novel compounds comprising three dicarboxylic acid diamide moieties interconnected to form a non-cyclic, monocyclic, bicyclic, tricyclic or polycyclic structure. Test devices such as test trips or ion-selective members are provided which contain hexacarboxylic acid hexa-amides as the ion-selective component. The test devices have a high selectivity for magnesium ions over alkali metal ions and other alkaline earth metal ions. Selectivity for magnesium ions over sodium and calcium ions permits determination of magnesium concentration in biological materials, including body fluids such as blood serum or whole blood. Magnesium concentration and activity can also be determined in sample solutions having a neutral or slightly acidic pH.

REFERENCES:
patent: 2130523 (1938-09-01), Carothers et al.
patent: 2130948 (1938-09-01), Carothers et al.
patent: 2163584 (1939-06-01), Carothers et al.
patent: 3957607 (1976-05-01), Simon et al.
patent: 4785111 (1988-11-01), Toda
patent: 4830671 (1989-05-01), Frihart et al.
Lanter et al. "Neutral Carrier Based Ion Selectivity Electrode or Intracellular Magnesium Activity Study", Analytical Chemistry, vol. 52, No. 14, 2400-2402 (Dec. 1980).
Erne et al., "Lipophilic Di- and Triamides as Ionophores for Alkaline Earthmetal Cations", Helvetia Chimica Acta, vol. 63, Fasc. 8, 2271-2279 (1980).
Erne et al., "Liphophilic Diamides as Ionophores for Alkali and Alkaline Earthmetal Cations", Helvetia Chimica Acta, vol. 65, Fasc. 2, 538-545 (1982).
Rouilly et al., "Neutral-Carrier-Based Magnesium-Selective Electrode", Analytical Chemistry, vol. 60, No. 19, 2013-2106 (Oct. 1988).
Muller et al., "Magnesium-Selective Electrodes for Blood Serum Studies and Water Hardness Measurement", Mikrochem. Acta [Vienna], vol. 3, 283-290 1988.

Affiliated with

Also associated with

Rating

Hexacarboxylic acid hexa-amides which form liphophilic complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hexacarboxylic acid hexa-amides which form liphophilic complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hexacarboxylic acid hexa-amides which form liphophilic complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-878405