Hexa-cyclic compound

Details Hexa-cyclic compound Hexa-cyclic compound

1997-12-12

1998-11-10

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 41, A61K 3140, A61K 31435, C07D47122

Patent

active

058344764

ABSTRACT:
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.

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