Hexa-cyclic compound

Details Hexa-cyclic compound Hexa-cyclic compound

1995-05-31

1997-06-10

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

558404, 558408, 558412, 558414, 560 24, 560 27, 560 28, 564209, 564210, 564212, 564305, 564306, 564307, 564308, 564428, C07C23305

Patent

active

056377703

ABSTRACT:
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.

REFERENCES:
patent: 5061795 (1991-10-01), Tagawa et al.
patent: 5071875 (1991-12-01), Horn et al.

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