Heteropolymeric protein production methods

Details Heteropolymeric protein production methods Heteropolymeric protein production methods

1991-10-16

1993-08-31

Low, Christopher S. F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 4351723, 4352402, 435 691, 536 2351, 536 235, 536 231, 935 6, 935 13, 935 66, 935 70, 935 34, 935 60, 935 61, 930110, C12P 2102, C12N 1516, C12N 1585

Patent

active

052408329

ABSTRACT:
Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.

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