Heteropolymeric protein production methods

Details Heteropolymeric protein production methods Heteropolymeric protein production methods

1995-05-31

1997-08-19

Low, Christopher S.F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 2351, 530395, 435360, 435325, 4353651, 435 691, 4353201, 4351723, 435366, 435363, C12P 2104, C12N 500

Patent

active

056587600

ABSTRACT:
Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.

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