Heterologous production of capreomycin and generation of new...

Details Heterologous production of capreomycin and generation of new... Heterologous production of capreomycin and generation of new...

2008-05-09

2011-10-25

Kim, Alexander (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S076000, C435S252100

Reexamination Certificate

active

08044186

ABSTRACT:
Provided are nucleic acid molecules comprising at least a functional fragment of the capreomycin biosynthetic gene cluster, polypeptides encoded by the cluster and recombinant host cells transformed with any of the nucleic acid molecules disclosed herein. Various methods using any of the vectors or expression cassettes that encode one or more of the gene products of the cluster are provided for heterologous production of capreomycin and capreomycin derivatives.

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