Heterogeneous topical compositions having a base of microgranule

Details Heterogeneous topical compositions having a base of microgranule Heterogeneous topical compositions having a base of microgranule

1988-12-07

1990-07-03

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424489, 424490, A61K 4700

Patent

active

049389629

ABSTRACT:
The present invention relates to a heterogeneous topical composition comprising microgranules or microparticles of a topically-acceptable caffeine metal carboxylate in a hydroalcoholic gel, as well as its preparation and use. The composition, which can be used as slenderizer and/or in the treatment of cellulitis, comprises a long acting topically-acceptable caffeine metal carboxylate as the active principle, which is present in the form of heterogeneously-distributed microgranules or microparticles, having a diameter of about 0.2 to 2 millimeters, suspended in a hydroalcoholic gel in which they are insoluble, advantageously together with Vitamin E or a derivative thereof.

REFERENCES:
patent: 3084104 (1963-04-01), Tuerck et al.
patent: 4698264 (1987-10-01), Steinke
patent: 4762707 (1988-08-01), Gergely et al.

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