Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1985-07-19
1987-06-02
Marantz, Sidney
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 56, 435 21, 435 25, 435 28, 436170, 436501, 436514, 436518, 436531, 436810, 436816, G01N 3350, G01N 33545, G01N 33558
Patent
active
046703810
ABSTRACT:
A heterogeneous, competitive binding immunoassay is conducted with a dry analytical element. The immunoassay is useful for determining a ligand (e.g. a therapeutic drug) and includes contacting a finite area of the element spreading layer with a sample of a liquid in the presence of a labeled ligand analog and an immobilized receptor. An immobilized ligand-receptor complex is formed within the finite area. Simultaneously, the uncomplexed ligand migrates horizontally away from the immobilized complex which remains in the center of the finite area. At least five seconds after the completion of the contacting, the amount of immobilized complex is measured in the center of the finite area.
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Danielson Susan J.
Dappen Glen M.
Frickey Paul H.
Sanford Karl J.
Sundberg Michael W.
Eastman Kodak Company
Marantz Sidney
Saunders David A.
Tucker J. Lanny
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