Heterogeneous immunoassay and reagent therefore

Details Heterogeneous immunoassay and reagent therefore Heterogeneous immunoassay and reagent therefore

1984-07-17

1987-01-27

Nucker, Christine M.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

435 7, 436528, 436529, 436530, 436531, 436532, 436533, 436534, 436825, 436826, G01N 33543, G01N 33544, G01N 33545, G01N 33546

Patent

active

046394257

ABSTRACT:
The invention is an improvement in a heterogeneous immunoassay, and reagent therefore, for the determination of a substance in a blood serum or plasma sample, such as a parnter of an immune reaction, in which one of the reaction partners is adsorbed on a solid carrier, the improvement comprises adding a detergent to the incubation medium of the reaction, in an amount of 0.0001 to 0.01% (w/v) to reduce interferences from the serum or plasma.

REFERENCES:
patent: 4200436 (1980-04-01), Mochida et al.
patent: 4241175 (1980-12-01), Miller et al.
patent: 4267270 (1981-05-01), Stout
patent: 4273756 (1981-06-01), Ling et al.
patent: 4273867 (1981-06-01), Lin et al.
patent: 4313927 (1982-02-01), Fridlender
patent: 4492762 (1985-01-01), Wang et al.
Chard, from Laboratory Techniques in Biochemistry and Molecular Biology, vol. 6, part 2, Work et al., eds., Elsevier Bio Medical, Amsterdam, 1982, p. 17.

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