Heterogeneous fluorescence assays using controlled pore glass pa

Details Heterogeneous fluorescence assays using controlled pore glass pa Heterogeneous fluorescence assays using controlled pore glass pa

1986-12-09

1988-10-25

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

436800, G01N 33552

Patent

active

047804238

ABSTRACT:
Improved heterogeneous fluorescence assays are provided which employ solid supports comprising controlled pore glass particles which are substantially transparent at both the wavelength used to excite the fluorescent probe used in the assay and at the emission wavelength of the probe. The assays achieve sensitivities comparable to those achieved with radioimmunoassays without the need to concentrate the particles prior to the fluorescent measurement as in prior art heterogeneous fluorescence assays employing other types of solid supports.

REFERENCES:
patent: 4197361 (1980-04-01), Hoff
patent: 4280992 (1981-07-01), Sugiura
patent: 4297337 (1981-10-01), Mansfield
patent: 4425438 (1984-01-01), Bauman
patent: 4680120 (1987-07-01), Ramsden

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