Heterofunctional polyethylene glycol and polyethylene oxide,...

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From heterocyclic reactant containing as ring atoms oxygen,...

Reexamination Certificate

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C524S612000, C528S405000

Reexamination Certificate

active

07009033

ABSTRACT:
Heterofunctional polyethylene glycol or polyethylene oxide, represented by one of the following formula (I) to (IV):wherein:m is an integer from 5 to 10,000;n is an integer from 1 to 20;each R is independently an organic substituent, preferably an hydrocarbon substituent that preferably comprises at least one heteroatom,each A is independently an alkyl, a substituted alkyl group or an hydrogen atom,and the salts thereof.

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Zalipsky, “Functionalized Poly(ethylene glycol) for Preparation of Biologically Relevant Conjugates,” Bioconjugate Chem., vol. 6, 1995, pp. 150-165.
Zalipsky et al., “Facile synthesis of alpha-hydroxy-omega-carboxymethylpolyethylene oxide,” Journal of Bioactive and Compatible Polymers, vol. 5, Apr. 1990, pp. 227-231.
CAPLUS accession No. 1978:51198 for the Makromolekulars Chemie article by Broze et al., “Some noew easy routes for the specific functionalization of polymers by pendant or end amino groups,” vol. 178, No. 11, 1977.
CAPLUS accession No. 2000:217495 for the Gaofenzi Tongbao article by Xiong et al., “Progress in synthesis of polyethylene glycol derivatives,” vol. 1, 2000.

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