Heterofunctional cellular immunological reagents, vaccines conta

Details Heterofunctional cellular immunological reagents, vaccines conta Heterofunctional cellular immunological reagents, vaccines conta

1994-12-08

1997-07-29

Cunningham, Thomas M.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Chemical modification or the reaction product thereof, e.g.,...

4241851, 4241931, 530300, 530350, 530402, C07K 14705, A61K 39385

Patent

active

056523424

ABSTRACT:
The present invention relates to a heterofunctional cellular immunological reagent comprising at least two T cell specific binding ligands covalently linked together, wherein one of the T cell specific binding ligands binds to a specific class or subclass of T cells and another of the T cell specific binding ligands is an antigen associated with disease or a causative agent of disease, or epitope thereof. The present invention also relates to vaccines containing the heterofunctional cellular immunological reagents and methods for the use of the same.

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