Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-04-11
2006-04-11
Landsman, Robert S. (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S069100, C435S252300, C435S320100, C435S325000, C435S471000
Reexamination Certificate
active
07026125
ABSTRACT:
This invention provides a purified heterodimer comprising an RXR and a hormone receptor. The invention also provides a method of screening ligands for their effect on the activity of an RXR-containing hormone receptor heterodimer comprising combining the heterodimer with the ligand and determining the effect on activity. Also provided is a method of amplifying the activity of a hormone receptor comprising forming a heterodimer with another hormone receptor.
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patent: WO 93/11235 (1993-06-01), None
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Pfahl Magnus
Zhang Xiao-kun
Landsman Robert S.
Ligand Pharmaceuticals
McDermott Will & Emery LLP
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