Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-10-10
2006-10-10
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007200, C435S235100, C435S441000
Reexamination Certificate
active
07118866
ABSTRACT:
Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a filamentous phage coat protein membrane anchor domain fused to at least one of the polypeptides.
REFERENCES:
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patent: 2095633 (1991-12-01), None
Better et al.,Escherichia coliSecretion of an Active Chimeric Antibody Fragment, 1988,Science, 240: pp. 1041-1043.
Chang et al., Expression of Antibody Fab Domains on Bacteriophage Surfaces, 1991,J. Immunol., 147: pp. 3610-3614.
Kabat et al.,Sequences of Proteins or Immunological Interest, 1987, U.S. Dept. HHS, 4thEdition pp. 494-525.
Winnacker,From Genes to Clones, 1987, VCH, Weinhein, Germany, pp. 276-279.
Winter et al., Man-made Antibodies, 1991,Nature, 349: pp. 293-299.
Barbas, III Carlos F.
Kang Angray
Lerner Richard A.
Fitting Thomas
McCarthy Michael J.
The Scripps Research Institute
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