Heterodimeric receptor libraries using phagemids

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

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4353201, 5303873, C12N 701, C12N 702, C12N 1572

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059553413

ABSTRACT:
Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an autogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a cpVIII membrane anchor domain fused to at least on of the polypeptides.

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