Heterodimeric conjugates of neomycin-chloramphenicol having...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S124000

Reexamination Certificate

active

07022839

ABSTRACT:
The present invention relates to heterodimeric conjugates of neomycin-chloramphenicol, of formula 1, their preparation and their use. Because of their heterodmieric structure, they can recognize both stem and loop of RNA motif and show binding ability to a certain RNA such that they have an enhanced pharmaceutical efficacy and reduced side effect which can be caused by non-specific drugs. For these reasons, they can be effectively used as an antiviral agent, an antibacterial agent or an anticancer drugs.

REFERENCES:
patent: 884713 (1908-04-01), Cherny
patent: 5143545 (1992-09-01), Stiffey et al.
patent: 5411941 (1995-05-01), Grinna et al.
patent: 6071515 (2000-06-01), Mezes et al.
patent: 6235469 (2001-05-01), Kang et al.
patent: 6316194 (2001-11-01), Karn et al.
Xavier et al. “RNA as a drug target: methods for biophysical characterization and screening,” TIBTECH Aug. 2000 (vol. 18), pp. 349-356.
Wells et al. “Pharacotherapy Handbook,” 2nd addition, 1998, pp. 375-381.
Bertram G. Katzung, Basic and Clinical Pharmacology, 7th edition, 1998, pp. 743-758.

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