Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-12-04
1999-07-13
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514365, 514444, 5462841, 544333, 548200, C07D40506, A61K 3144
Patent
active
059227400
ABSTRACT:
Heterocyclyclcarbonyl substituted benzofuranyl-ureas are prepared by reacting heterocyclylcarbonyl substituted 3-amino-benzofuranes with appropriate isocyanates or isothiocyanates. The unsubstituted ureas are transferred into substituted ureas by usual methods of substitution. The heterocyclylcarbonyl substituted benzofuranyl-ureas are useful as active ingredients in medicaments particularly for the treatment of acute and chronical inflammatory processes.
REFERENCES:
patent: 4745127 (1988-05-01), Atkinson et al.
Biochem.J. 291, 389-395 (1993).
Biochem.Pharmacol. 42, 153-162 (1991).
Eur.J.Pharmacol. 127, 105-115, 1986.
Braunlich Gabriele
Es-Sayed Mazen
Fischer Rudiger
Fugmann Burkhardt
Henning Rolf
Bayer Aktiengesellschaft
Fan Jane
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