Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-06
2006-06-06
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S335000, C514S338000, C514S341000, C514S349000, C514S350000, C514S364000, C514S374000, C514S383000, C514S394000, C514S406000, C514S414000, C514S416000, C514S417000, C546S201000, C546S268100, C546S272100, C546S275400, C546S275700, C546S293000, C546S297000, C546S298000, C548S110000, C548S128000, C548S234000, C548S262800, C548S309700, C548S375100, C548S466000, C548S472000, C548S477000
Reexamination Certificate
active
07056932
ABSTRACT:
The invention is concerned with novel heterocyclyl substituted 1-alkoxy acetic acid derivatives of formula (I)wherein R1to R6and A are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.
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Banner et al., STN International (2005) HCAPLU Database, Accession No. 2004:467862, Reg. No. 701265-25-0.
Hilpert K., et al.,Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors, Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 37, No. 23 pp. 3889-3901 (1994), XP000561935.
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Gobbi Luca Claudio
Groebke Zbinden Katrin
Mohr Peter
Obst Ulrike
Freistein Andrew B.
Hoffman-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
Saeed Kamal A.
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