Heterocyclyl compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S218000, C514S222500, C514S253010, C514S253120, C540S489000, C540S492000, C544S003000, C544S006000, C544S230000, C544S360000, C544S363000, C544S364000, C544S372000

Reexamination Certificate

active

08071586

ABSTRACT:
The invention is concerned with novel heterocyclyl compounds of formula (I)wherein A, X, Y1, Y2, Y3, R3, R4, R5, R6, R7, R8, R9, R10, m, n and p are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medicaments.

REFERENCES:
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patent: 2007/0249589 (2007-10-01), Aebi et al.
patent: 1627876 (2006-02-01), None
patent: WO 00/32590 (2000-06-01), None
patent: WO 2008/136754 (2008-11-01), None
Vice et al., J. Org. Chem., 66, pp. 2487-2492 (2001).
Brown Ripin et al., Tetrahedron Letters, 41, pp. 5817-5819 (2000).
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Koshti et al., Tetrahedron Letters, 35, pp. 5157-5160 (1994).
Sugiyama et al., J. Am. Chem. Soc., 129, pp. 14811-14817 (2007).
Radosevich et al., J. Am. Chem. Soc, 127, pp. 1090-1091 (2005).

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