Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-09-06
2005-09-06
Powers, Fiona T. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S428000, C548S557000, C548S567000
Reexamination Certificate
active
06939891
ABSTRACT:
The invention relates to certain novel compounds having Vanilloid Receptor (VR1) antagonist activity, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders.
REFERENCES:
patent: 3424760 (1969-01-01), Helsley et al.
patent: 3424761 (1969-01-01), Helsley et al.
Pan P-C et al., “Soluble Polymer-Supported Synthesis of Arylpiperazines” Tetrahedron Letters, Elsevier Science Publishers, Amsterdam, NL, vol. 39, No. 51, Dec. 17, 1998, pp. 9505-9508, XP004144238.
Hesley et al., “Synthesis and biological activity of some 1-substituted 3-pyrrolidinylureas” Journal of Medicinal Chemistry, vol. 11, No. 5, 1968, pp. 1034-1037, XP001095126.
Rami Harshad Kantilal
Thompson Mervyn
Wyman Paul Adrian
Kinzig Charles
McCarthy Mary
Powers Fiona T.
Simon Soma G.
SmithKline Beecham PLC
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