Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-02-12
2000-05-16
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483054, A61K 314184, C07D23530, C07D23528, C07D23826, C07D23524
Patent
active
06063801&
ABSTRACT:
The invention provides a topoisomerase poison of formula I: ##STR1## wherein R.sub.1 -R.sub.8 have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof.
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LaVoie
Kim Jung Sun
LaVoie Edmond J.
Liu Leroy Fong
Rangarajan Meera
Morris Patricia L.
Rutgers The State University of New Jersey
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