Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-07-15
2008-07-15
McKane, Joseph (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S313100
Reexamination Certificate
active
11035005
ABSTRACT:
Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia:wherein, R1is lower alkyl, substituted lower alkyl, phenyl, substituted phenyl, benzyl, substituted benzyl, benzyloxy, substituted benzyloxy, or SO2R5; R5is phenyl, substituted phenyl, heterocycle, substituted heterocycle, alkyl, or substituted alkyl; R2is lower alkyl, substituted lower alkyl, CF3, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, or cycloalkyl; R3is hydrogen, lower alkyl, or substituted lower alkyl; R4is phenyl, substituted phenyl, heterocycle, substituted heterocycle, thiophene, or substituted thiophene; R6is hydrogen, lower alkyl, substituted lower alkyl, CF3, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, cycloalkyl, or substituted cycloalkyl; W, X and Y are independently CR7or N; and R7is hydrogen, halogen, lower alkyl, or substituted lower alkyl.
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Berkowitz Joshua D.
Caggiano Thomas Joseph
Huryn Donna M.
Kreft Anthony Frank
Kubrak Dennis Martin
Barrett Rebecca R.
Chung Susannah
Howson & Howson LLP
McKane Joseph
Wyeth
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